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Itahana K et al (2007) Targeted inactivation of Mdm2 RING nger E3 ubiquitin ligase activityin the mouse reveals mechanistic insights into p53 regulation. The GST-A1 polymorphism shows different frequencies for the variantallele between Caucasian and African (respectively 17 and 11%) and Asian (1%) populations.For GST-A2, three coding non-synonymous SNPs have been described: rs2234951 G>A,rs2180314 C>G, rs6577 T>G that lead to changes respectively in the residues on GST-A2protein at position 110, 112 and 210

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